Research on the effects of Aronia on our immune system

Black chokeberry

Black chokeberry (Aronia melanocarpa)

 proven in Russian folk medicine for decades

The black chokeberry or chokeberry originally comes from North America where it was used by the Potawatomi Indian tribe to heal colds.[1] At the beginning of the 20th century the plant came to the Soviet Union and Europe. In Russia and Eastern Europe in particular, it has been used as a medicinal plant for decades in conventional medicine and folk medicine, for infectious and childhood diseases such as measles or scarlet fever, high blood pressure, treatment of gastric, intestinal, glandular and liver and gallbladder diseases, stomach inflammation and vitamin deficiency diseases, radiation diseases, Poisoning by heavy metals and used for somatic radiation damage [2]

Research confirms the versatility

Black chokeberry can discharge heavy metals and protect against radioactive rays, has antioxidant, anti-inflammatory, antiviral, cancer-fighting, anti-atherosclerotic, antihypertensive, anti-platelet and anti-diabetic properties as well as anti-diabetic properties.[3]

Antioxidant Properties

Black chokeberry has strong antioxidant [4] and radical scavenging properties of any berry. [5] [6] therefore it can be effectively used in the prophylaxis and treatment of health disorders associated with oxidative stress, particularly radiation sickness,[7] cancer [8] and diabetes. [9]

Anti-inflammatory

Because of their strong anti-inflammatory properties,Black chokeberry products canpathological conditions associated with inflammatory processes such as diabetes [10] cardiovascular diseases [11] skin diseases [12] eye diseases [13] immune system disorders [14]  [15] protect.

Detoxification

Black chokeberry can remove toxins and prevent damage to health.
Cadmium - inhibition of damage to kidneys[16] [17] Liver tissue [18] bone[19] [20] Reduced cadmium storage in the brain,[21] blood, liver, kidneys, bones,[22] osteoprotective effect[23]
Lead - Reduced concentration in internal organs, bone tissue and urine, provides complete protection of the liver from histological changes[24] [25] [26]
Alcohol consumption - protection of the stomach, liver and nerves [27] [28] [29]  inhibition of gastric ulcers and lipid peroxidation in the lungs, liver and small intestine [30] reduces anxiety and depression [31]
Nitroso compounds - (tobacco smoke, smoked meat, milk powder, fertilizers, children's toys made from natural and synthetic rubber) Black chokeberry a prevents the production of carcinogenic nitroso compounds [32] [33]
Herbicides -
 polyphenolic compounds present in chokeberry such as chlorogenic acid, quercetin and kaempferol provide protection from paraquat [34] [35]  Mustard gas and its derivatives (chemo) - oral and topical administration of anthocyanins present in chokeberry and quercetin inhibits the damage to red blood cells, lungs, small intestine, liver, spleen and skin [36] [37] 7,12-dimethylbenzo (a) anthracene,[38] detoxification in the liver[39]
Methamphetamines (Crystal Meth) - Chlorogens and caftaric acids can damage liver and protect erythrocytes from oxidative stress.[40]
Tobacco smoke - chokeberry extract inhibits liver degeneration caused by tobacco smoke, pathological tissue changes in the lungs, development of lung tumors[41], erythrocytes, bone marrow and weight loss [42] [43] [44] Generation and release of superoxide radicals [45] and damage to osteoblasts by scavenging the radicals, improving bone mass, stability and fracture healing.[46]

Black chokeberry can alleviate many side effects of medicines

Amiodarone [47] - Pneumotoxicity [48], Indomethacin [49] - gastric lining damage [50] Cisplatin [51] - Kidney cell cytotoxicity [52] Cyclophosphamide [53] and ziprasidone [54] - Decrease in the activities of antioxidant enzymes in healthy cells[55] [56]  Paracetamol [57]- Hepatorenal toxicity in liver and kidney tissues [58]  Rifampicin [59] and isoniazid [60]- liver damage [61] Etoposide [62]- apoptotic HL-60 cells [63]

Disease prevention

Black chokeberry are rich in polyphenols, which are among the most important antioxidants and protect the body from free radicals and thus from various diseases.
Diabetes regulates blood sugar levels [64] [65] increases the effectiveness of insulin [66] and lowers diabetes risk [67] [68]
Cardiovascular diseases Aronia inhibits blood clotting [69] [70] [71], normalized  Blood pressure [72] [73] [74], protects the arteries [75] [76] [77] and heart muscle [78]  protects from metabolic syndrome (obesity, high blood pressure and impaired lipid metabolism) and inhibits the progress of this condition [79] [80] [81] 

Cancer Black chokeberry products prevent cancer development, after two days of administration of chokeberry extract tumor cell growth is inhibited by 50% [82], protect healthy cells from free radicals, increase the effectiveness of cancer drugs [83], accumulate cyanidin glycosides in tumor cells and allow death of cells with carcinogenic changes. [84]  Consumption of chokeberry products Protects against side effects of drugs used in chemotherapy, administration of chokeberry extract increases the level of low-molecular thiols in plasma in cancer patients treated with chemotherapy to the value of healthy subjects [85]. The positive effect of aronia has been proven in pancreatic[86]  Colon [87] [88] [89] [90] Chest- [91] [92] [93] Pulmonary [94] cervical cancer [95] Brain tumor - glioblastoma [96] (aronia extract causes a down-regulation of matrix metalloproteinases MMP-2, MMP-12, MMP-16, MMP-17 in the U 373 glioblastoma cells)[97] leukemia (also in chemotherapy-resistant leukemia) [98] [99] 

Digestive system disorders 

Black chokeberry Protection against digestive disorders such as fatty liver disease [100] [101] [102] Cirrhosis [103] gastric ulcer [104]

Other health problems

Black chokeberry  products can include cellulite, edema [105] prevent obesity and overweight [106] [107] in male infertility [108] [109] Prostate enlargement [110] depression [111], anxiety [112], complicated pregnancies [113] help.

Children under 3 years of age should not eat Black chokeberry. They are also not recommended for people who have blood clotting problems or gastritis. Because of the antihypertensive properties of the berries, people with low blood pressure should also be careful. [114] Consultation with a doctor is recommended.



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[114] Черноплодная рябина, или арония Мичурина, – действительно уникальное растение. Хотя она относится к тому же семейству, что и красная рябина, близкими родственниками они не являются.
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