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Research on the influence of honey in cosmetics on the immune system of our skin
Raw untreated honey
A wound healing agent with a long tradition
The healing properties of honey are based on the fact that it has antibacterial, antifungal and antiviral effects, maintains a moist wound condition and forms a protective barrier against infections due to its high viscosity.
Honey has been valued since ancient times in many cultures as a remedy for numerous skin diseases as well as for wound healing. The oldest writing, in which honey is mentioned, is an approx. 4000 year old clay tablet of the Sumerians with prescriptions for ointments and medicines [1].
Honey is able to cancel antibiotic resistances.
Honey is increasingly used in the treatment of skin diseases and infected wounds, where conventional pharmaceutical products fail.[2] Honey is also used in the treatment of skin diseases and infected wounds. Thanks to its broad spectrum of phytoncides, honey inhibits the growth of pathogenic microorganisms or has been shown to destroy all previously tested microorganisms, including dreaded antibiotic-resistant bacteria such as Staphylococcus aureus in chronic wounds or the yeast Candida albicans.[3] Following the use of honey, infections with previously antibiotic-resistant bacteria can be effectively treated with antibiotics.[4] [5]
Research:
Honey as a wound dressing
supports healing processes and stimulates the body's immune responses[6] [7], destroys pathogens naturally and is very effective in treating acne, cuts, burns, bruises and wounds with risk of infection[8]. Honey eliminates infection, debridement, suppresses inflammation, minimizes scarring, stimulates angiogenesis, tissue granulation, epithelial growth[9] [10] and relieves pain[11]. Physicians used honey to treat ulcers, burns, fistulas, and boils[12], as well as almost all types of wounds such as abrasion, abscess, amputation, decubitus, burns, chills, burst abdominal wound, cracked nipples, fistulas, diabetic, malignant, leprosy, traumatic, cervical spasm, sickle cell, and septic wounds.[13] [14] Studies in Fournier's gangrene confirm rapid improvement with decreased edema and discharge, faster regeneration and less or no scarring, effective wound debridement, and decrease in mortality[15].
Honey for fungal infections
Honey has antifungal activity against all common dermatophytes[16] [17], inhibits toxin production[18], bacterial infections[19] and is effective in treating seborrheic dermatitis and dandruff [20].
Antiviral activity of honey
Honey is safe and effective against herpes labialis, herpes genitalis[21] and rubella virus[22] compared to aciclovir.[22]
Honey in ophthalmology
Honey is used worldwide to treat various diseases of the eye and surrounding structures such as corneal injuries, conjunctivitis, blepharitis, keratitis, chemical burns, and thermal burns [23] [24].
The application of honey in infectious conjunctivitis reduced the redness, swelling and pus discharge until the complete eradication of the pathogen from the body. [25] [26]
[1] Geschichte der Wundbehandlung mit Honig, Deutscher Ärzteverlag ZFA Z Allg. Med 2015, 91(4)
[2] Mandal MD, Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pac J Trop Biomed. 2011;1(2):154-160. doi:10.1016/S2221-1691(11)60016-6
[PMC]
[3] Cooper R. Honey in wound care: antibacterial properties. GMS Krankenhhyg Interdiszip. 2007;2(2):Doc51. Published 2007 Dec 28
[PMC]
[4] McLoone P, Oluwadun A, Warnock M, Fyfe L. Honey: A Therapeutic Agent for Disorders of the Skin. Cent Asian J Glob Health. 2016;5 (1):241. Published 2016 Aug 4.
[PMC]
[5] McLoone P, Warnock M, Fyfe L. Honey: A realistic antimicrobial for disorders of the skin. J Microbiol Immunol Infect. 2016;49(2):161-167.
[Science Direct]
[6] Medhi B, Puri A, Upadhyay S, Kaman L. Topical application of honey in the treatment of wound healing: a meta analysis. JK Sci . 2008;10:166–169.
[jkscience.org]
[7] Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J, Tonks A. Honey stimulates inflammatory cytokine production from monocytes. Cytokine. 2003;21:242–247.
[PubMed]
[8] Dr. S. Mladenov, The Preservative Effect of Honey, Pchelarstvo Magazine, issue 12, 1967
[honeypedia]
[9] Comparison of the antibacterial activity of honey from different provenance against bacteria usually isolated from skin wounds. Basualdo C, Sgroy V, Finola MS, Marioli JM Vet Microbiol. 2007 Oct 6; 124(3-4):375-81.
[PubMed]
[10] Medhi B, Puri A, Upadhyay S, Kaman L. Topical application of honey in the treatment of wound healing: a meta analysis. JK Sci . 2008;10:166–169.
[jkscience]
[11] Topical application of honey in treatment of burns. Subrahmanyam M Br J Surg. 1991 Apr; 78(4):497-8.
[PubMed]
[12] Honey-a remedy rediscovered and its therapeutic utility. Bansal V, Medhi B, Pandhi P Kathmandu Univ Med J (KUMJ). 2005 Jul-Sep; 3(3):305-9.
[PubMed]
[13] Clinical observations on the wound healing properties of honey. Efem SE Br J Surg. 1988 Jul; 75(7):679-81.
[PubMed]
[14] Mixture of honey, beeswax and olive oil inhibits growth of Staphylococcus aureus and Candida albicans. Al-Waili NS Arch Med Res. 2005 Jan-Feb; 36(1):10-3.
[PubMed]
[15] Predisposing factors and treatment outcome in Fournier's gangrene. Analysis of 28 cases. Gürdal M, Yücebas E, Tekin A, Beysel M, Aslan R, Sengör F Urol Int. 2003; 70(4):286-90.
[PubMed]
[16] Sampath Kumar KP, Bhowmik D, Chiranjib , Biswajit , Chandira MR. Medicinal uses and health benefits of Honey: An overview. J Chem Pharm Res . 2010;2:385–395.
[jocpr]
[17] . Brady NF, Molan PC, Harfoot CG. The sensitivity of dermatophytes to the antimicrobial activity of manuka honey and other honey. J Pharm Sci. 1997;2:1–3.
[Wiley Online Library]
[18] Effect of honey on antibody production against thymus-dependent and thymus-independent antigens in primary and secondary immune responses. Al-Waili NS, Haq A J Med Food. 2004 Winter; 7(4):491-4.
[PubMed]
[19] Honey--a remedy rediscovered and its therapeutic utility. Bansal V, Medhi B, Pandhi P Kathmandu Univ Med J (KUMJ). 2005 Jul-Sep; 3(3):305-9.
[PubMed]
[20] Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. Al-Waili NS Eur J Med Res. 2001 Jul 30; 6(7):306-8.
[PubMed]
[21] Investigating the antimicrobial activity of natural honey and its effects on the pathogenic bacterial infections of surgical wounds and conjunctiva. Al-Waili NS J Med Food. 2004 Summer; 7(2):210-22.
[PubMed]
[22] Effect of honey on antibody production against thymus-dependent and thymus-independent antigens in primary and secondary immune responses. Al-Waili NS, Haq AJ Med Food. 2004 Winter; 7(4):491-4.
[PubMed]
[23] Therapeutic uses of honey and honeybee larvae in central Burkina Faso. Meda A, Lamien CE, Millogo J, Romito M, Nacoulma OG J Ethnopharmacol. 2004 Nov; 95(1):103-7.
[PubMed]
[24] Traditional medicine in oman: its role in ophthalmology. Shenoy R, Bialasiewicz A, Khandekar R, Al Barwani B, Al Belushi H Middle East Afr J Ophthalmol. 2009 Apr; 16(2):92-6.
[PubMed]